1. Tubing, Valves & Fittings Lab Supplies For Sale
  2. sku: 10777668945612853
  3. MILLIPORE MCOSP027H1

MILLIPORE MCOSP027H1 Millistak Hc Pro Filter Area MCOSP014H1 0.14M

Mcosp014h1 Millipore Mcosp027h1 Millistak Hc Pro Filter Pod - 0.14m Surface Area

( Brand: Millipore ), ( Manufacturer Part Number: MCOSP027H1 ), ( Part Type: Filter Area ), ( Intended Use/discipline: Biological Laboratory ), ( Unit Type: Unit )

Review MILLIPORE Millistak Hc Pro Filter Pod 0.14m Surface Area

The **Millipore MILLI-STAK HC Pro Filter (MCOSP027H1)** and its complementary **0.14 m (MCOSP014H1) variant** represent a cutting-edge solution in sterile filtration, engineered to deliver uncompromising performance for laboratory, bioprocessing, and pharmaceutical applications where contamination control is paramount. These high-capacity, high-efficiency filters are designed within MilliporeSigma s advanced **MILLI-STAK HC Pro** series, a modular, stackable system that combines the reliability of depth filtration with the precision of absolute sterility. The **MCOSP027H1** features a **0.27 m filtration area**, while the **MCOSP014H1** offers a more compact **0.14 m configuration**, both utilizing a **hydrophobic, 0.2 m pore size** membrane crafted from **polyethersulfone (PES)**, a material renowned for its chemical resistance, durability, and compatibility with a wide range of solvents, buffers, and aqueous solutions. This PES membrane ensures superior retention of bacteria, pyrogens, and particulate matter while maintaining low extractables and leachables, critical for applications in cell culture, vaccine production, and sterile filtration of sensitive biologics. The **HC Pro** design incorporates a **high-capacity, depth-filtering pre-layer** that extends filter life by capturing larger particles and reducing membrane clogging, thereby enhancing flow rates and operational efficiency. The filters are housed in a **sterile, single-use, disposable cartridge format**, eliminating the need for cleaning or sterilization between uses, which minimizes cross-contamination risks and simplifies workflows. Their **stackable and scalable nature** allows for flexible integration into existing filtration systems, accommodating varying flow demands while maintaining consistent performance. Additionally, the **MILLI-STAK HC Pro** system is engineered with **low-binding properties**, making it ideal for applications involving proteins, antibodies, or other sensitive biomolecules where adsorption or denaturation must be minimized. The filters are validated for **sterility, integrity, and bacterial retention**, adhering to stringent industry standards such as **USP **, **ISO 8573-4**, and **FDA guidelines**, ensuring compliance with the most rigorous regulatory requirements. Whether used for **cell culture media sterilization, bioreactor feed filtration, or pharmaceutical-grade liquid processing**, these filters provide a robust, high-throughput solution that balances efficiency, reliability, and sterility in demanding laboratory and manufacturing environments.

**Pros and Cons of Purchasing Millipore MCOSP027H1 (Millistak HC Pro Filter) and MCOSP014H1 (0.14 m Area)**

### **Pros**

1. **High Efficiency and Reliability**

The Millistak HC Pro filter is designed for high-capacity sterile filtration, ensuring consistent removal of bacteria, particles, and endotoxins. The 0.1-micron pore size is ideal for applications requiring strict sterility, such as cell culture, biopharmaceuticals, and sensitive laboratory procedures.

2. **Durability and Longevity**

Millipore s filters are engineered with robust materials, including hydrophobic polypropylene, which resists chemical degradation and maintains structural integrity over repeated use. The reinforced construction reduces the risk of filter collapse during high-flow applications.

3. **Compatibility with Sterile Processing**

The filter is designed for sterile filtration, making it suitable for use in cleanrooms, aseptic environments, and pharmaceutical manufacturing. It can be sterilized via autoclaving (if specified by the manufacturer) or gamma irradiation, ensuring contamination-free performance.

4. **Wide Application Range**

The 0.14 m filter (MCOSP014H1) is versatile for small-scale to medium-scale processes, including:

- Cell culture media sterilization

- Buffer and reagent filtration

- Sample preparation in molecular biology

- Pharmaceutical and biotech formulations

5. **Low Leakage and High Clarity**

The hydrophobic membrane minimizes adsorption of proteins and other biologics, reducing the risk of carryover contamination. This ensures high recovery rates of target molecules while maintaining sterility.

6. **Easy Integration into Systems**

The filter is compatible with standard filtration systems, including vacuum manifolds, peristaltic pumps, and dead-end filtration setups. Its design allows for straightforward installation and replacement.

7. **Regulatory Compliance**

Millipore products are widely used in industries regulated by **FDA, EU GMP, and ISO standards**, ensuring that the filter meets stringent quality and safety requirements.

---

### **Cons**

1. **Cost**

Millipore filters, especially high-quality sterile-grade options, are more expensive than generic or lower-grade alternatives. The upfront cost may be prohibitive for small labs or startups with limited budgets.

2. **Single-Use Nature**

Most sterile filters are designed for single-use only, which increases operational costs over time. Disposal of used filters contributes to waste generation, though some facilities may have recycling programs.

3. **Potential for Membrane Fouling**

While hydrophobic, the membrane can still foul with certain contaminants (e.g., proteins, oils, or particulate matter), reducing flow rates and requiring more frequent replacements. Pre-filtration may be necessary to extend filter life.

4. **Limited Flow Rates for Large Volumes**

The 0.14 m filter has a relatively small surface area, which may limit its efficiency for high-volume applications. Larger-scale processes may require multiple filters or higher-capacity models (e.g., 0.5 m or 1.0 m ).

5. **Sensitivity to Improper Handling**

The filter must be stored properly (e.g., in sealed packaging, away from moisture and extreme temperatures) to prevent contamination or degradation. Mishandling can compromise sterility and performance.

6. **Vendor Dependency**

Millipore (now part of **Merck**) is a trusted brand, but reliance on proprietary products may limit flexibility if alternative suppliers are preferred. Some labs may seek generic equivalents, though these may not always meet the same quality standards.

7. **Potential for Autoclave Damage (If Applicable)**

While some Millistak filters are autoclave-compatible, others may degrade under high heat or pressure. Always verify the manufacturer s guidelines to avoid damaging the filter during sterilization.

---

### **Conclusion**

The **Millipore MCOSP027H1 (Millistak HC Pro Filter) and MCOSP014H1 (0.14 m )** are excellent choices for applications requiring **high sterility, reliability, and regulatory compliance**. Their durability, efficiency, and compatibility with critical processes make them a preferred option in **biopharmaceuticals, cell culture, and sensitive laboratory work**. However, their **higher cost, single-use nature, and potential fouling risks** must be weighed against budget constraints and operational needs.

For **small-scale or cost-sensitive applications**, evaluating alternatives (e.g., generic 0.22-micron filters or larger-area Millipore options) may be worthwhile. Conversely, if **sterility, consistency, and regulatory adherence** are paramount, the investment in Millipore filters is justified.

---

### **Recommendation**

- **Purchase if:**

- Your application demands **sterile filtration with minimal contamination risk** (e.g., cell culture, pharmaceuticals, biotech).

- You operate in a **regulated environment** (FDA, EU GMP) where brand reliability is critical.

- You can justify the **higher cost** based on long-term efficiency and reduced risk of process failure.

- **Consider alternatives if:**

- Your budget is **limited**, and generic filters meet your sterility needs.

- You require **higher flow rates or larger volumes**, in which case a **larger-area Millipore filter (e.g., 0.5 m )** or a different membrane type (e.g., PES) may be more suitable.

- You frequently encounter **fouling issues**, and pre-filtration or a different membrane chemistry (e.g., hydrophilic) could improve performance.

For most **high-stakes sterile filtration applications**, the **Millipore Millistak HC Pro remains a strong recommendation** due to its proven track record. However, always **compare total cost of ownership** (including filter lifespan, flow rates, and maintenance) before finalizing a purchase.

Details:

This item is brand new and factory-sealed in its original packaging. This depth filter provides salable performance and consistent results across batches, ideal for bio manufacturing environments. The box is in excellent condition with all manufacturer labeling intact. Optimize your downstream bio processing with the Millipore Millistak HC Pro filter, designed for high-capacity clarification in pod format.

Model: MCOSP027H1: Millistak HC Pro COSP 0.27m Depth Filter Format: Pod Format condition: New in box Quantity: 1 pod Includes: Certificate of Quality inside original sealed.

part #: mcosp027h1 price

  • $201.52

specifications tubinglabsupplyu:

  • brand: Millipore
  • mpn: Mcosp027h1
  • part type: Filter Area
  • intended use/discipline: Biological Laboratory
  • unit type: Unit

returns tubinglabsupplyu:

  • paid by: Buyer
  • policy: Returns Accepted
  • method: Money back
  • time: 30 Days

payments tubinglabsupplyu:

  • other
  • credit card: Mastercard
  • wallet: Paypal

shipping tubinglabsupplyu:

  • cost: $0.00
  • service: UPS Ground, Expedited
  • transit: 5-8 Days
  • carrier: UPS
  • type: Fixed
  • class: Standard, Expedited

seller tubinglabsupplyu:

  • # reviews: 1668
  • city: Fairfield, California
  • rating: 99.9%

general tubinglabsupplyu:

  • condition: Used
  • Healthcare, Lab Dental > Medical, Lab Dental Supplies > Other Medical, Lab Dental Supplies

offer tubinglabsupplyu:

  • availability: In Stock
  • options: Ship-to-home
  • sold: 0
  • started: February 13, 2026
  • quantity: 1
part type: filter area, intended use/discipline: biological laboratory, unit type: unit,
category: business & industrial > healthcare, lab dental > medical, lab dental supplies, sku: 10777668945612853,
Millipore MCOSP027H1 Is Similar To:
tubinglabsupplyu logo
1 offer $201.52 USD
  • New. Offer #1 priced at $201.52 + $12.99 shipping estimate = $214.51* total. Write a review. Millistak+ HC Pro Pod Depth Filter.+$12.99 shipping

Copyright © tubinglabsupplyu.com